Research and News
Recent preclinical research has produced encouraging preliminary data supporting the use of cord blood stem cells as a potential therapy for conditions such as cerebral palsy, brain injury, juvenilediabetes, and hearing loss. Recent updates on clinical applications of cord blood are summarized in this 2011 article from Experimental Hematology.
More information can be found below in a selected sample of papers published in peer-reviewed journals, presentations from major medical meetings, and media coverage of the emerging data involving cord blood stem cell studies and regenerative medicine applications.
Animal and human studies are investigating the potential of using one's own cord blood stem cells to improve conditions associated with neurological damage, such as anoxic brain injury at birth, cerebral palsy, traumatic brain injury, and stroke.
Clinical Trial in Juvenile Diabetes
The University of Florida is conducting a clinical trial to determine the potential of cord blood stem cells to regenerate insulin production in juvenile diabetes patients.
- The University of Texas Health Science Center at Houston (UTHealth) is actively recruiting for the first Phase I safety study investigating the use of a child’s own umbilical cord blood stem cells for traumatic brain injury in children. The study is being performed in conjunction with Children’s Memorial Hermann Hospital, UTHealth’s primary children’s teaching hospital.
o TBI study protocol on Clinical Trials.gov
o Aprecursor to this study involved treating children who
Study results published in March, 2011 Neurosurgery
Television segment of University of Texas neurologist and clinical researcher James E. Baumgartner, M.D. discussing the potential of cord blood stem cells to treat traumatic brain injury
Dr. Charles Cox, University of Texas Pediatric Surgeon and clinical researcher, outlines how cord blood is being used to treat children with all types of brain injury.
A collection of stories about one child’s progress after being diagnosed with Cerebral Palsy as an infant and receiving an autologous transplant.
had suffered traumatic brain injury with their own bon
marrow stem cells.
- Cord Blood Changed My Daughter's Life
- Girl's Own Cord Blood Used to Treat Her Brain Injury
- Chloe’s progress – Hippotherapy and starting kindergarten
Recruiting is underway for a Phase 1 study at Children’s Memorial Hermann Hospital investigating the use of a child’s own cord blood stem cells to treat acquired hearing loss. This first-of-its-kind intervention is researching the ability of the cord blood stem cells to stimulate cellular repair and restore hearing.
- Hearing Loss trial protocol on clinicaltrials.gov
- Read a study published in Cell Transplantation (2008) demonstrating that animal subjects whose hearing was damaged and were treated with cord blood stem cells showed significant healing to the damaged portion of the inner ear.
Juvenile Diabetes (also known as Type 1 Diabetes)
Studies are underway at The University of Florida investigating the potential of cord blood stem cells to preserve insulin production in patientswith juvenile diabetes.
Studies are currently underway investigating the ability of cord blood stem cells to differentiate into a wide variety of cell types including bone, cartilage and heart tissue.
According to research presented at the 2008 American Heart Association Scientific Sessions, children with heart defects may someday receive perfectly-matched new heart valves built using stem cells from their umbilical cord blood.
Foundations of Cord Blood Stem Cell Science